PUBLICATIONS 2020-03-10T00:27:29+00:00

Selected recent publications:

*Xie, W., *Jiao, B., *Bai, Q., *Ilin, V. A., Sun, M., Burton, C. E., Kolodieznyi, D., Calderon, M. J., Stolz, D. B., Opresko, P. L., St. Croix, C. M., Watkins, S. C., Van Houten, B., Bruchez, M. P., and Burton, E. A. (2020) Chemoptogenetic ablation of neuronal mitochondria in vivo with spatiotemporal precision and controllable severity. eLife (*equal contribution, joint first authors)

Dukes, A. D., Bai, Q., Van Laar, V. S., Zhou, Y., Ilin, V., David, C. N., Agim, Z. S., Bonkowsky, J. L., Cannon, J. R., Watkins, S. C., St. Croix, C. M., Burton, E. A. and Berman, S. B. (2016)  Live imaging of mitochondrial dynamics in CNS dopaminergic neurons in vivo demonstrates early reversal of mitochondrial transport following MPP+ exposure.  Neurobiology of Disease 95:238-249  [Burton E. A. and Berman S. B. are joint corresponding authors] https://www.ncbi.nlm.nih.gov/pubmed/27452482

Di Maio, R. Barrett, P. J., Hoffman, E. K., Barrett, C. W., Zharikov, A., Borah, A., Hu, X., McCoy, J., Chu, C. T., Burton, E. A., Hastings, T. G., Greenamyre, J. T. (2016) α-Synuclein binds TOM20 and inhibits mitochondrial protein import in Parkinson’s disease.  Science Translational Medicine.  8:342ra78:1-14
https://www.ncbi.nlm.nih.gov/pubmed/27280685

Zharikov, A., Cannon, J. R., Tapias, V., Bai, Q., Horowitz, M. P., Shah, V., El Ayadi, A., Hastings, T. G., Greenamyre, J. T., Burton, E. A. (2015) shRNA targeting α-synuclein prevents neurodegeneration in a Parkinson’s disease model.  Journal of Clinical Investigation. 125(7):2721-2735 [Featured as a “Scientific Show Stopper” with accompanying commentary on JCI website] https://www.ncbi.nlm.nih.gov/pubmed/26075822

Keatinge, M., Bui, H., Menke, A., Chen, Y.-C., Sokol, A. M., Bai, Q., Ellett, F., Da Costa, M., Burke, D., Gegg, M., Trollope, L., Payne, T., McTighe, A., Mortiboys, H., de Jager, S., Nuthhall, H., Kuo, M.-S., Fleming, A., Schapira, A., Renshaw, S., Highley, J., R., Chacinska, A., Panula, P., Burton, E. A., O’Neil, M., Bandmann, O. (2015) Early inflammation and alpha-synuclein-independent cell death in glucocerebrosidase 1 deficient Danio rerio.  Human Molecular Genetics. 24(23):6640-52
https://www.ncbi.nlm.nih.gov/pubmed/26376862

Bai, Q., Parris, R. S., Burton, E. A. (2014)  Different Mechanisms Regulate Expression of Zebrafish Myelin P0 in Myelinating Oligodendrocytes and its Induction Following Axonal Injury.  J Biol Chem.  289(35):24114-28. [Featured on the cover of the August 29, 2014 issue of JBC] https://www.ncbi.nlm.nih.gov/pubmed/25028515

Zhou, Y., Cattley, R. T., Cario, C. L., Bai, Q., Burton, E. A. (2014)  Quantification of larval zebrafish motor function in multi-well plates using open-source MATLAB applications.  Nature Protocols. 9(7):1533-1548 [Featured on the cover of the July 2014 issue of Nature Protocols] https://www.ncbi.nlm.nih.gov/pubmed/24901738

Burton E. A. (2014) Zebrafish.  In Movement Disorders: Genetics and Models, M. Le Doux ed. (Amsterdam: Elsevier) ISBN: 978-0-12-405195-9
https://www.elsevier.com/books/movement-disorders/ledoux/978-0-12-405195-9

Milanese, C., Sager, J. J., Bai, Q., Farrell, T. C., Cannon, J. R., Greenamyre, J. T., Burton, E. A. (2012)  Hypokinesia and reduced dopamine levels in zebrafish lacking β- and γ1-synucleins.  J Biol Chem.  287(5):2971-83 [Featured on the cover of the January 27, 2012 issue of JBC] https://www.ncbi.nlm.nih.gov/pubmed/22128150

Sager, J.J., Torres, G.E., Burton, E. A. (2012) The zebrafish homologue of the human DYT1 dystonia gene is widely expressed in CNS neurons but non-essential for early motor system development.  PLoS ONE. 7(9):e45175
https://www.ncbi.nlm.nih.gov/pubmed/23028827

Cario, C. L., Farrell, T. C., Milanese, C. and Burton, E. A. (2011).  Automated measurement of zebrafish larval movement.  The Journal of Physiology.  589(15), 3703-8.
https://www.ncbi.nlm.nih.gov/pubmed/21646414

Farrell, T. C., Cario, C. L., Milanese, C., Vogt, A., Jeong, J.-H., Burton, E. A. (2011) Evaluation of spontaneous propulsive movement as a screening tool to detect rescue of Parkinsonism phenotypes in zebrafish models.  Neurobiology of Disease.  44(1), 9-18.[Featured on the cover of the October 2011 issue of NBD] https://www.ncbi.nlm.nih.gov/pubmed/21669287

Bandmann, O. and Burton, E. A. (2010).  Genetic zebrafish models of neurodegenerative diseases. Neurobiol Dis. 40(1), 58-65
https://www.ncbi.nlm.nih.gov/pubmed/20493258

Bai, Q., Garver, J. A., Hukriede, N. A., Burton, E. A. (2007).  Generation of a transgenic zebrafish model of Tauopathy using a novel promoter element derived from the zebrafish eno2 gene. Nucleic Acids Res. 35 (19), 6501-16
https://www.ncbi.nlm.nih.gov/pubmed/17897967

 

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